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Tbio
EMILIN2
EMILIN-2

Protein Summary
Description
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254528
  • ENSP00000254528
  • ENSG00000132205

Symbol
  • FOAP-10
  • EMILIN-2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.79
cell type or tissue
0.76
PubMedID
0.72
histone modification site profile
0.71
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.22   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.22   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
NELL2
Tbio
Family:  Enzyme
Novelty:  0.03760438
p_int:  0.999998838
p_ni:  0.000001157
p_wrong:  5e-9
Score:  0.185
Data Source:  BioPlex,STRINGDB
OS9
Tbio
Novelty:  0.01490339
p_int:  0.999976478
p_ni:  0.000023466
p_wrong:  5.7e-8
Data Source:  BioPlex
PLAC9
Tdark
Novelty:  0.23764669
p_int:  0.999190267
p_ni:  0.000809719
p_wrong:  1.4e-8
Data Source:  BioPlex
CCL3L1
Tbio
Novelty:  0.01124082
p_int:  0.999167691
p_ni:  0.000831168
p_wrong:  0.000001141
Data Source:  BioPlex
PCDHGB4
Tdark
Novelty:  0.25018904
p_int:  0.998748427
p_ni:  0.001247986
p_wrong:  0.000003588
Data Source:  BioPlex
NELL1
Tbio
Family:  Enzyme
Novelty:  0.01325888
p_int:  0.998704077
p_ni:  0.001295891
p_wrong:  3.2e-8
Score:  0.173
Data Source:  BioPlex,STRINGDB
MFAP5
Tbio
Novelty:  0.01839035
p_int:  0.99715806
p_ni:  0.002841047
p_wrong:  8.93e-7
Data Source:  BioPlex
DEFA5
Tbio
Novelty:  0.00863727
p_int:  0.994764086
p_ni:  0.001088104
p_wrong:  0.00414781
Data Source:  BioPlex
PCDHB11
Tdark
Novelty:  0.80480462
p_int:  0.992964757
p_ni:  0.007035229
p_wrong:  1.4e-8
Data Source:  BioPlex
RETNLB
Tbio
Novelty:  0.00777842
p_int:  0.984718326
p_ni:  0.015280091
p_wrong:  0.000001583
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
2
2
86.7
BMI-adjusted waist-hip ratio
3
2
3
86.6
red blood cell distribution width
2
2
2
81
mean reticulocyte volume
1
1
1
64.4
apolipoprotein A 1 measurement
1
1
1
61.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
2
86.7
BMI-adjusted waist-hip ratio
3
86.6
red blood cell distribution width
2
81
mean reticulocyte volume
1
64.4
apolipoprotein A 1 measurement
1
61.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
elastin microfibril interfacer 2
VGNC:13258
739134
Macaque
elastin microfibril interfacer 2
695758
Mouse
MGI:2389136
246707
Rat
RGD:1305343
316736
Dog
elastin microfibril interfacer 2
VGNC:40344
100684071
Species
Name
OMA
EggNOG
Inparanoid
Chimp
elastin microfibril interfacer 2
Macaque
elastin microfibril interfacer 2
Mouse
Rat
Dog
elastin microfibril interfacer 2
Publication Statistics
PubMed Score 3.22
PubMed score by year
PubTator Score 9.43
PubTator score by year
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Related Publications
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PMID
Year
Title