Protein Summary
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
- ENST00000254528
- ENSP00000254528
- ENSG00000132205
- FOAP-10
- EMILIN-2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.79 | ||
cell type or tissue | 0.76 | ||
PubMedID | 0.72 | ||
histone modification site profile | 0.71 | ||
transcription factor perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.22 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 55 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.22 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 55 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (26)
NELL2
Family: Enzyme
Novelty: 0.03760438
p_int: 0.999998838
p_ni: 0.000001157
p_wrong: 5e-9
Score: 0.185
Data Source: BioPlex,STRINGDB
OS9
Novelty: 0.01490339
p_int: 0.999976478
p_ni: 0.000023466
p_wrong: 5.7e-8
Data Source: BioPlex
PLAC9
Novelty: 0.23764669
p_int: 0.999190267
p_ni: 0.000809719
p_wrong: 1.4e-8
Data Source: BioPlex
CCL3L1
Novelty: 0.01124082
p_int: 0.999167691
p_ni: 0.000831168
p_wrong: 0.000001141
Data Source: BioPlex
PCDHGB4
Novelty: 0.25018904
p_int: 0.998748427
p_ni: 0.001247986
p_wrong: 0.000003588
Data Source: BioPlex
NELL1
Family: Enzyme
Novelty: 0.01325888
p_int: 0.998704077
p_ni: 0.001295891
p_wrong: 3.2e-8
Score: 0.173
Data Source: BioPlex,STRINGDB
MFAP5
Novelty: 0.01839035
p_int: 0.99715806
p_ni: 0.002841047
p_wrong: 8.93e-7
Data Source: BioPlex
DEFA5
Novelty: 0.00863727
p_int: 0.994764086
p_ni: 0.001088104
p_wrong: 0.00414781
Data Source: BioPlex
PCDHB11
Novelty: 0.80480462
p_int: 0.992964757
p_ni: 0.007035229
p_wrong: 1.4e-8
Data Source: BioPlex
RETNLB
Novelty: 0.00777842
p_int: 0.984718326
p_ni: 0.015280091
p_wrong: 0.000001583
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (1)
Components (4)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Disease Associations (null)
GWAS Traits (12)
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
waist-hip ratio | 1 | 2 | 2 | 86.7 | |||||
BMI-adjusted waist-hip ratio | 3 | 2 | 3 | 86.6 | |||||
red blood cell distribution width | 2 | 2 | 2 | 81 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 64.4 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 61.4 | |||||
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
waist-hip ratio | 2 | 86.7 | |||||
BMI-adjusted waist-hip ratio | 3 | 86.6 | |||||
red blood cell distribution width | 2 | 81 | |||||
mean reticulocyte volume | 1 | 64.4 | |||||
apolipoprotein A 1 measurement | 1 | 61.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | elastin microfibril interfacer 2 | VGNC:13258 | 739134 | |||||
Macaque | elastin microfibril interfacer 2 | 695758 | ||||||
Mouse | MGI:2389136 | 246707 | ||||||
Rat | RGD:1305343 | 316736 | ||||||
Dog | elastin microfibril interfacer 2 | VGNC:40344 | 100684071 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | elastin microfibril interfacer 2 | |||||
Macaque | elastin microfibril interfacer 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | elastin microfibril interfacer 2 | |||||
Publication Statistics
PubMed Score 3.22
PubMed score by year
PubTator Score 9.43
PubTator score by year
Related Publications
Text Mined References (21)
GeneRif Annotations (11)
Items per page:
0 of 0
PMID | Year | Title |
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