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Tdark
EMC9
ER membrane protein complex subunit 9

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216799
  • ENSP00000216799
  • ENSG00000100908
  • ENST00000419198
  • ENSP00000403210
  • ENST00000642147
  • ENSP00000494976
  • ENSG00000285377
  • ENST00000646772
  • ENSP00000495623

Symbol
  • C14orf122
  • FAM158A
  • CGI-112
  • FAM158A
  • C14orf122
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.79
tissue sample
0.66
cellular component
0.65
transcription factor
0.62
cell type or tissue
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.1   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 42   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.1   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 42   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
EMC3
Tbio
Novelty:  0.01113829
p_int:  1
Score:  0.999
Data Source:  BioPlex,STRINGDB
EMC2
Tbio
Novelty:  0.05843267
p_int:  0.999999998
p_ni:  2e-9
Score:  0.999
Data Source:  BioPlex,STRINGDB
EMC7
Tdark
Novelty:  0.28771768
p_int:  0.999999987
p_ni:  1.3e-8
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC6
Tbio
Novelty:  0.18299013
p_int:  0.999996177
p_ni:  0.000002814
p_wrong:  0.00000101
Score:  0.997
Data Source:  BioPlex,STRINGDB
EMC10
Tbio
Novelty:  0.04986528
p_int:  0.999891768
p_ni:  0.000108231
p_wrong:  1e-9
Score:  0.998
Data Source:  BioPlex,STRINGDB
EMC1
Tbio
Novelty:  0.05360812
p_int:  0.999673169
p_ni:  0.000326831
Score:  0.999
Data Source:  BioPlex,STRINGDB
EMC4
Tbio
Novelty:  0.12174476
p_int:  0.998352274
p_ni:  0.000165069
p_wrong:  0.001482659
Score:  0.997
Data Source:  BioPlex,STRINGDB
MMGT1
Tdark
Novelty:  0.20333677
p_int:  0.998000058
p_ni:  0.00199994
p_wrong:  3e-9
Score:  0.996
Data Source:  BioPlex,STRINGDB
OGA
Tchem
Family:  Enzyme
Novelty:  0.00035723
p_int:  0.977776227
p_ni:  0.022223773
Score:  0.188
Data Source:  BioPlex,STRINGDB
EMC8
Tdark
Novelty:  0.2452967
Score:  0.906
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (22)
Items per page:
1 – 5 of 22
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
2
2
75
platelet count
2
2
2
75
mean corpuscular volume
2
2
2
62
mean corpuscular volume
2
2
2
62
mean corpuscular hemoglobin concentration
1
1
1
55.2
Items per page:
1 – 5 of 22
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
75
platelet count
2
75
mean corpuscular volume
2
62
mean corpuscular volume
2
62
mean corpuscular hemoglobin concentration
1
55.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 9
VGNC:3436
744829
Macaque
ER membrane protein complex subunit 9
715192
Mouse
MGI:1934682
85308
Rat
RGD:1308113
290224
Dog
ER membrane protein complex subunit 9
VGNC:40338
480257
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 9
Macaque
ER membrane protein complex subunit 9
Mouse
Rat
Dog
ER membrane protein complex subunit 9
Publication Statistics
PubMed Score 2.10
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title