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Tdark
EMC7
ER membrane protein complex subunit 7

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000256545
  • ENSP00000256545
  • ENSG00000134153

Symbol
  • C11orf3
  • C15orf24
  • HT022
  • C11orf3
  • C15orf24
  • ORF1-FL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
transcription factor perturbation
0.94
histone modification site profile
0.92
kinase perturbation
0.76
transcription factor binding site profile
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 44   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (71)
EMC3
Tbio
Novelty:  0.01113829
p_int:  1
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC9
Tdark
Novelty:  0.52441743
p_int:  0.999999987
p_ni:  1.3e-8
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC2
Tbio
Novelty:  0.05843267
p_int:  0.999996396
p_ni:  0.000003604
Score:  0.993
Data Source:  BioPlex,STRINGDB
EMC8
Tdark
Novelty:  0.2452967
p_int:  0.999954925
p_ni:  0.000045075
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC6
Tbio
Novelty:  0.18299013
p_int:  0.999863248
p_ni:  0.000136752
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC10
Tbio
Novelty:  0.04986528
p_int:  0.998966362
p_ni:  0.001033007
p_wrong:  6.31e-7
Score:  0.997
Data Source:  BioPlex,STRINGDB
EMC1
Tbio
Novelty:  0.05360812
p_int:  0.988583394
p_ni:  0.011416606
Score:  0.995
Data Source:  BioPlex,STRINGDB
APOA2
Tbio
Novelty:  0.00117627
p_int:  0.97977133
p_ni:  0.020228663
p_wrong:  7e-9
Data Source:  BioPlex
EMC4
Tbio
Novelty:  0.12174476
p_int:  0.973544657
p_ni:  0.026455073
p_wrong:  2.71e-7
Score:  0.996
Data Source:  BioPlex,STRINGDB
MMGT1
Tdark
Novelty:  0.20333677
p_int:  0.968036673
p_ni:  0.031963328
Score:  0.995
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 7
VGNC:2489
453298
Macaque
ER membrane protein complex subunit 7
695440
Mouse
MGI:1920274
73024
Dog
ER membrane protein complex subunit 7
VGNC:40336
478242
Horse
ER membrane protein complex subunit 7
VGNC:17557
100057906
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 7
Macaque
ER membrane protein complex subunit 7
Mouse
Dog
ER membrane protein complex subunit 7
Horse
ER membrane protein complex subunit 7
Publication Statistics
PubMed Score 2.83
PubMed score by year
PubTator Score 0.13
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title