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Tbio
EMC6
ER membrane protein complex subunit 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000248378
  • ENSP00000248378
  • ENSG00000127774
  • ENST00000397133
  • ENSP00000380322

Symbol
  • TMEM93
  • TMEM93
  • RAB5IFL
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
histone modification site profile
0.78
cellular component
0.74
disease perturbation
0.74
cell type or tissue
0.7


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.13   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.13   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
EMC9
Tdark
Novelty:  0.52441743
p_int:  0.999996177
p_ni:  0.000002814
p_wrong:  0.00000101
Score:  0.997
Data Source:  BioPlex,STRINGDB
EMC3
Tbio
Novelty:  0.01113829
p_int:  0.999986492
p_ni:  0.000013508
Score:  0.989
Data Source:  BioPlex,STRINGDB
EMC8
Tdark
Novelty:  0.2452967
p_int:  0.999983923
p_ni:  0.000016077
Score:  0.997
Data Source:  BioPlex,STRINGDB
P01911
Tchem
Novelty:  0.00240724
p_int:  0.999918848
p_ni:  0.000078952
p_wrong:  0.0000022
Score:  0.221
Data Source:  BioPlex,STRINGDB
EMC7
Tdark
Novelty:  0.28771768
p_int:  0.999863248
p_ni:  0.000136752
Score:  0.996
Data Source:  BioPlex,STRINGDB
NADSYN1
Tbio
Family:  Enzyme
Novelty:  0.0445844
p_int:  0.999843136
p_ni:  0.00000227
p_wrong:  0.000154594
Data Source:  BioPlex
EMC10
Tbio
Novelty:  0.04986528
p_int:  0.999334382
p_ni:  0.000665617
p_wrong:  1e-9
Score:  0.98
Data Source:  BioPlex,STRINGDB
GOLPH3L
Tbio
Novelty:  0.30373124
p_int:  0.998759278
p_ni:  0.001240588
p_wrong:  1.34e-7
Data Source:  BioPlex
EMC4
Tbio
Novelty:  0.12174476
p_int:  0.997626611
p_ni:  0.002373159
p_wrong:  2.3e-7
Score:  0.994
Data Source:  BioPlex,STRINGDB
REEP6
Tbio
Novelty:  0.10645981
p_int:  0.997344216
p_ni:  0.002655784
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 6
VGNC:9271
454433
Macaque
ER membrane protein complex subunit 6
707030
Mouse
MGI:1913298
66048
Rat
RGD:1309231
287477
Dog
ER membrane protein complex subunit 6
VGNC:40335
100856142
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ER membrane protein complex subunit 6
Macaque
ER membrane protein complex subunit 6
Mouse
Rat
Dog
ER membrane protein complex subunit 6
Publication Statistics
PubMed Score 7.13
PubMed score by year
PubTator Score 3.87
PubTator score by year
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Related Publications
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PMID
Year
Title