Tbio EMC1 ER membrane protein complex subunit 1

Protein Summary

Description

This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2012]

Uniprot Accession IDs

• Q8N766
• A8K6F3
• Q14700
• Q5TG62
• Q63HL0
• Q63HL3
• Q8NBH8

Gene Name

• EMC1

Ensembl ID

• ENST00000375199
• ENSP00000364345
• ENSG00000127463
• ENST00000375208
• ENSP00000364354
• ENST00000477853
• ENSP00000420608

Symbol

• KIAA0090
• CAVIPMR
• KIAA0090

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
histone modification site profile	0.81
kinase perturbation	0.81
cell type or tissue	0.8
cellular component	0.71

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.83   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 165   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.83   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 165   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0