ELOVL1
Elongation of very long chain fatty acids protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 1 | ||
disease perturbation | 0.95 | ||
transcription factor binding site profile | 0.69 | ||
histone modification site profile | 0.67 | ||
transcription factor | 0.65 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Fatty acid metabolism | ||||
Reactome | Fatty acyl-CoA biosynthesis | ||||
Reactome | Linoleic acid (LA) metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Fatty acid metabolism | ||||
Fatty acyl-CoA biosynthesis | ||||
Linoleic acid (LA) metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 2 | 4 | 4 | 92.3 | |||||
platelet crit | 2 | 3 | 4 | 88.5 | |||||
systolic blood pressure | 1 | 1 | 1 | 71.9 | |||||
cognitive function measurement | 1 | 1 | 1 | 47.7 | |||||
asparaginase-induced acute pancreatitis | 1 | 1 | 0 | 4.6 | 30.2 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 4 | 92.3 | |||||
platelet crit | 4 | 88.5 | |||||
systolic blood pressure | 1 | 71.9 | |||||
cognitive function measurement | 1 | 47.7 | |||||
asparaginase-induced acute pancreatitis | 0 | 4.6 | 30.2 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ELOVL fatty acid elongase 1 | VGNC:529 | 456820 | |||||
Macaque | ELOVL fatty acid elongase 1 | 700557 | ||||||
Mouse | MGI:1858959 | 54325 | ||||||
Rat | RGD:1587151 | 679532 | ||||||
Dog | ELOVL fatty acid elongase 1 | VGNC:40319 | 100855761 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ELOVL fatty acid elongase 1 | |||||
Macaque | ELOVL fatty acid elongase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ELOVL fatty acid elongase 1 | |||||
PMID | Year | Title |
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