ELF2
ETS-related transcription factor Elf-2
Protein Summary
Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. Isoform 2 may function in repression of RUNX1-mediated transactivation.
- ENST00000358635
- ENSP00000351458
- ENSG00000109381
- ENST00000379549
- ENSP00000368867
- ENST00000379550
- ENSP00000368868
- ENST00000394235
- ENSP00000377782
- ENST00000510408
- ENSP00000426997
- NERF
- EU32
- NERF
- NERF-2
- NERF-1A
- NERF-1B
- NERF-1a,b
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 0.87 | ||
interacting protein | 0.74 | ||
microRNA | 0.66 | ||
kinase perturbation | 0.6 | ||
tissue | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.75 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 135 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.75 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 135 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0