EIF2B3
Translation initiation factor eIF-2B subunit gamma
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.84 | ||
interacting protein | 0.79 | ||
histone modification site profile | 0.74 | ||
biological process | 0.68 | ||
tissue | 0.63 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cap-dependent Translation Initiation | ||||
Reactome | Eukaryotic Translation Initiation | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Recycling of eIF2:GDP | ||||
Reactome | Translation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cap-dependent Translation Initiation | ||||
Eukaryotic Translation Initiation | ||||
Metabolism of proteins | ||||
Recycling of eIF2:GDP | ||||
Translation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
intraocular pressure measurement | 1 | 1 | 0 | 7 | 54.4 | ||||
BMI-adjusted hip circumference | 1 | 1 | 1 | 15.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
intraocular pressure measurement | 0 | 7 | 54.4 | ||||
BMI-adjusted hip circumference | 1 | 15.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | eukaryotic translation initiation factor 2B subunit gamma | VGNC:7401 | 456543 | |||||
Macaque | eukaryotic translation initiation factor 2B subunit gamma | 705862 | ||||||
Mouse | MGI:1313286 | 108067 | ||||||
Rat | RGD:620821 | 171145 | ||||||
Dog | eukaryotic translation initiation factor 2B subunit gamma | VGNC:40262 | 475379 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | eukaryotic translation initiation factor 2B subunit gamma | |||||
Macaque | eukaryotic translation initiation factor 2B subunit gamma | |||||
Mouse | ||||||
Rat | ||||||
Dog | eukaryotic translation initiation factor 2B subunit gamma | |||||
PMID | Year | Title |
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