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Tdark
EHBP1L1
EH domain-binding protein 1-like protein 1

Protein Summary
Description
May act as Rab effector protein and play a role in vesicle trafficking.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309295
  • ENSP00000312671
  • ENSG00000173442
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
transcription factor
0.79
transcription factor binding site profile
0.68
transcription factor perturbation
0.68
tissue sample
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.89   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 14   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.89   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 14   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
FRMD8
Tdark
Novelty:  0.39375892
Score:  0.786
Data Source:  STRINGDB
SSSCA1
Tdark
Novelty:  0.53523038
Score:  0.769
Data Source:  STRINGDB
TIGD3
Tdark
Novelty:  1.23642174
Score:  0.769
Data Source:  STRINGDB
KCNK7
Tdark
Family:  IC
Novelty:  0.25673931
Score:  0.71
Data Source:  STRINGDB
FAM89B
Tbio
Novelty:  0.10306021
Score:  0.688
Data Source:  STRINGDB
CDC42EP2
Tbio
Novelty:  0.21932639
Score:  0.684
Data Source:  STRINGDB
MAP3K11
Tchem
Family:  Kinase
Novelty:  0.01112378
Score:  0.658
Data Source:  STRINGDB
DPF2
Tbio
Family:  Epigenetic
Novelty:  0.0403366
Score:  0.625
Data Source:  STRINGDB
BIN1
Tbio
Novelty:  0.00312612
Score:  0.614
Data Source:  STRINGDB
LTBP3
Tbio
Novelty:  0.0190763
Score:  0.573
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (40)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
5
97.8
heel bone mineral density
3
5
7
95.1
urate measurement
3
3
3
93.3
mean platelet volume
3
2
3
93.2
BMI-adjusted waist-hip ratio
5
4
6
90.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
5
97.8
heel bone mineral density
7
95.1
urate measurement
3
93.3
mean platelet volume
3
93.2
BMI-adjusted waist-hip ratio
6
90.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EH domain binding protein 1 like 1
VGNC:1051
744408
Macaque
EH domain binding protein 1 like 1
721918
Mouse
MGI:3612340
114601
Rat
RGD:1563823
309169
Dog
EH domain binding protein 1 like 1
VGNC:40245
483734
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EH domain binding protein 1 like 1
Macaque
EH domain binding protein 1 like 1
Mouse
Rat
Dog
EH domain binding protein 1 like 1
Publication Statistics
PubMed Score 2.89
PubMed score by year
PubTator Score 1.90
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title