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Tbio
EGFLAM
Pikachurin

Protein Summary
Description
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322350
  • ENSP00000313084
  • ENSG00000164318
  • ENST00000336740
  • ENSP00000337607
  • ENST00000354891
  • ENSP00000346964
  • ENST00000397202
  • ENSP00000380385
  • ENST00000397210
  • ENSP00000380393
  • ENST00000506135
  • ENSP00000425579
  • ENST00000514476
  • ENSP00000423228

Symbol
  • AGRINL
  • AGRNL
  • PIKA
  • PIKA
  • AGRNL
  • AGRINL
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
gene perturbation
0.85
protein domain
0.85
cell type or tissue
0.77
cell line
0.76


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 76.21   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 99   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 76.21   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0