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Tbio
EEF1AKMT2
EEF1A lysine methyltransferase 2

Protein Summary
Description
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368836
  • ENSP00000357829
  • ENSG00000203791

Symbol
  • C10orf138
  • METTL10
  • Efm4
  • METTL10
  • C10orf138
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (55)
EEF1A1
Tchem
Novelty:  0.00059953
Score:  0.961
Data Source:  Reactome,STRINGDB
EEF2KMT
Tbio
Family:  Enzyme
Novelty:  0.33892681
Score:  0.875
Data Source:  STRINGDB
ETFBKMT
Tbio
Family:  Enzyme
Novelty:  0.33247149
Score:  0.811
Data Source:  STRINGDB
VCPKMT
Tbio
Family:  Enzyme
Novelty:  0.37849297
Score:  0.811
Data Source:  STRINGDB
CSKMT
Tdark
Family:  Enzyme
Novelty:  0.79226766
Score:  0.802
Data Source:  STRINGDB
EEF1AKMT1
Tbio
Family:  Enzyme
Novelty:  0.22249584
Score:  0.8
Data Source:  STRINGDB
NDUFAF7
Tbio
Family:  Enzyme
Novelty:  0.24691414
Score:  0.782
Data Source:  STRINGDB
METTL13
Tbio
Family:  Enzyme
Novelty:  0.15986409
Score:  0.782
Data Source:  STRINGDB
METTL21A
Tbio
Family:  Enzyme
Novelty:  0.31897774
Score:  0.77
Data Source:  STRINGDB
METTL18
Tdark
Family:  Enzyme
Novelty:  0.3377377
Score:  0.767
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (44)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
2
2
2
96.8
glomerular filtration rate
7
5
6
6.6
94.3
brain volume measurement
11
7
11
91
1
2
2
90.8
2
2
1
1.2
90.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
2
96.8
glomerular filtration rate
6
6.6
94.3
brain volume measurement
11
91
2
90.8
1
1.2
90.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EEF1A lysine methyltransferase 2
VGNC:4746
450807
Fruitfly
FBgn0031485
33504
S.cerevisiae
S000001326
854746
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EEF1A lysine methyltransferase 2
Fruitfly
S.cerevisiae
Publication Statistics
PubMed Score 8.03
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
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