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Tbio
ECHDC1
Ethylmalonyl-CoA decarboxylase

Protein Summary
Description
Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368289
  • ENSP00000357272
  • ENSG00000093144
  • ENST00000368291
  • ENSP00000357274
  • ENST00000430841
  • ENSP00000402492
  • ENST00000454591
  • ENSP00000404866
  • ENST00000454859
  • ENSP00000401751
  • ENST00000474289
  • ENSP00000434908
  • ENST00000528402
  • ENSP00000436109
  • ENST00000531967
  • ENSP00000436585

Symbol
  • MMCD
  • HEL-S-76
  • dJ351K20.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
cell type or tissue
0.71
histone modification site profile
0.71
transcription factor binding site profile
0.71
transcription factor perturbation
0.68


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.16   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.16   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0