You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
NPIPB8
Nuclear pore complex-interacting protein family member B8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000529716
  • ENSP00000434399
  • ENSG00000255524
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.77
tissue
0.64
cell line
0.31
protein domain
0.15
gene perturbation
0.09


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.32   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.32   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (7)
1 – 7 of 7
C2orf74
Tdark
Novelty:  1.10883293
Score:  0.59
Data Source:  STRINGDB
ZNF280D
Tdark
Family:  TF
Novelty:  1.31551539
Score:  0.543
Data Source:  STRINGDB
SIRPG
Tbio
Novelty:  0.10364764
Score:  0.476
Data Source:  STRINGDB
SYS1
Tbio
Novelty:  0.03311919
Score:  0.471
Data Source:  STRINGDB
HMG20A
Tbio
Family:  TF
Novelty:  0.11994252
Score:  0.448
Data Source:  STRINGDB
DEXI
Tbio
Novelty:  0.04132772
Score:  0.443
Data Source:  STRINGDB
BSND
Tbio
Novelty:  0.01638636
Score:  0.416
Data Source:  STRINGDB
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
3
10
5
6.5
83.4
red blood cell density measurement
1
1
1
81.6
body fat percentage
1
1
2
68
C-reactive protein measurement
1
1
1
66.3
platelet count
2
2
2
65.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
5
6.5
83.4
red blood cell density measurement
1
81.6
body fat percentage
2
68
C-reactive protein measurement
1
66.3
platelet count
2
65.7
Publication Statistics
PubMed Score 0.32
PubMed score by year
PubTator Score 0.31
PubTator score by year