You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
DVL3
Segment polarity protein dishevelled homolog DVL-3

Protein Summary
Description
Involved in the signal transduction pathway mediated by multiple Wnt genes. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313143
  • ENSP00000316054
  • ENSG00000161202
  • ENST00000431765
  • ENSP00000405885
  • ENST00000649964
  • ENSP00000497134

Symbol
  • KIAA0208
  • DRS3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
biological process
0.84
microRNA
0.76
cell type or tissue
0.72
pathway
0.71


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.04   (req: < 5)
Gene RIFs: 28   (req: <= 3)
Antibodies: 289   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.04   (req: >= 5)
Gene RIFs: 28   (req: > 3)
Antibodies: 289   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 21
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0