Tbio DTYMK Thymidylate kinase

Protein Summary

Description

Catalyzes the conversion of dTMP to dTDP.

Uniprot Accession IDs

• P23919
• B7ZW70
• Q6FGX1
• Q9BUX4

Gene Name

• DTYMK

Ensembl ID

• ENST00000305784
• ENSP00000304802
• ENSG00000168393

Symbol

• CDC8
• TMPK
• TYMK
• CDC8
• TMPK
• TYMK
• PP3731

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	1
virus perturbation	0.99
interacting protein	0.98
transcription factor perturbation	0.97
molecular function	0.94

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Nucleotide Kinase / Thymidylate Kinase

DTO Classes

Protein / Kinase / Non-protein Kinase / Nucleotide Kinase / Thymidylate Kinase Family / Thymidylate Kinase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 150.23   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 403   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 150.23   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 403   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0