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Tdark
DRC3
Dynein regulatory complex subunit 3

Protein Summary
Description
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313838
  • ENSP00000326870
  • ENSG00000171962
  • ENST00000399182
  • ENSP00000382136
  • ENST00000399187
  • ENSP00000382140
  • ENST00000584166
  • ENSP00000462661

Symbol
  • LRRC48
  • LRRC48
  • CFAP134
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.6   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.6   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0