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Tdark
DQX1
ATP-dependent RNA helicase DQX1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393951
  • ENSP00000377523
  • ENSG00000144045
  • ENST00000404568
  • ENSP00000384621
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
protein domain
0.73
tissue sample
0.71
gene perturbation
0.68
disease perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (226)
MYO9A
Tbio
Novelty:  0.09467086
p_int:  0.994981633
p_ni:  0.005018366
p_wrong:  2e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
LRIF1
Tdark
Novelty:  0.26861958
p_int:  0.994702615
p_ni:  0.005297385
Score:  0.161
Data Source:  BioPlex,STRINGDB
MYO5C
Tbio
Novelty:  0.05680943
p_int:  0.991679477
p_ni:  0.008320523
Data Source:  BioPlex
PSMG4
Tdark
Novelty:  0.05339077
p_int:  0.987788866
p_ni:  0.012209871
p_wrong:  0.000001263
Data Source:  BioPlex
MYO9B
Tbio
Novelty:  0.0164265
p_int:  0.981764403
p_ni:  0.018235597
Score:  0.186
Data Source:  BioPlex,STRINGDB
KIF1A
Tbio
Novelty:  0.00505209
p_int:  0.948897139
p_ni:  0.051091485
p_wrong:  0.000011376
Score:  0.248
Data Source:  BioPlex,STRINGDB
APPBP2
Tbio
Novelty:  0.14742368
p_int:  0.939325256
p_ni:  0.060672092
p_wrong:  0.000002652
Data Source:  BioPlex
FBXO30
Tdark
Novelty:  0.60394319
p_int:  0.930193129
p_ni:  0.069806871
Score:  0.189
Data Source:  BioPlex,STRINGDB
PER1
Tbio
Novelty:  0.01290576
p_int:  0.91645322
p_ni:  0.083542795
p_wrong:  0.000003985
Data Source:  BioPlex
PEAK1
Tchem
Family:  Kinase
Novelty:  0.02919858
p_int:  0.893545505
p_ni:  0.106454495
Score:  0.179
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
1
1
64.9
body height
1
1
1
59.9
platelet crit
1
1
1
59
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
64.9
body height
1
59.9
platelet crit
1
59
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DEAQ-box RNA dependent ATPase 1
VGNC:226
470409
Macaque
DEAQ-box RNA dependent ATPase 1
709749
Mouse
MGI:2136388
93838
Rat
RGD:1591766
680434
Dog
DEAQ-box RNA dependent ATPase 1
VGNC:40086
475784
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DEAQ-box RNA dependent ATPase 1
Macaque
DEAQ-box RNA dependent ATPase 1
Mouse
Rat
Dog
DEAQ-box RNA dependent ATPase 1
Publication Statistics
PubMed Score 2.47
PubMed score by year
PubTator Score 1.25
PubTator score by year
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Related Publications
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PMID
Year
Title