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Tbio
DPYSL5
Dihydropyrimidinase-related protein 5

Protein Summary
Description
May have a function in neuronal differentiation and/or axon growth. This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288699
  • ENSP00000288699
  • ENSG00000157851
  • ENST00000401478
  • ENSP00000385549
  • ENST00000614712
  • ENSP00000481305

Symbol
  • CRMP5
  • ULIP6
  • CRAM
  • CRMP5
  • Ulip6
  • CRMP-5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.74
microRNA
0.68
histone modification site profile
0.66
PubMedID
0.58
transcription factor
0.54


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 217.45   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 207   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 217.45   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 207   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0