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Tbio
DPY19L1
Probable C-mannosyltransferase DPY19L1

Protein Summary
Description
Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310974
  • ENSP00000308695
  • ENSG00000173852
  • ENST00000612226
  • ENSP00000478865

Symbol
  • GA0500
  • KIAA0877
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
transcription factor perturbation
0.97
kinase perturbation
0.95
disease perturbation
0.83
microRNA
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.09   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 140   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.09   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
LDLRAD4
Tbio
Novelty:  0.04881486
p_int:  0.999997733
p_ni:  0.000002265
p_wrong:  1e-9
Data Source:  BioPlex
LYPD3
Tbio
Novelty:  0.03248533
p_int:  0.999994157
p_ni:  0.000005843
Data Source:  BioPlex
SCN3B
Tbio
Family:  IC
Novelty:  0.0438123
p_int:  0.999934093
p_ni:  0.000065907
Data Source:  BioPlex
TNFRSF8
Tclin
Novelty:  0.00030231
p_int:  0.999928798
p_ni:  0.000071202
Data Source:  BioPlex
SEMA7A
Tbio
Novelty:  0.00741605
p_int:  0.999795039
p_ni:  0.000204283
p_wrong:  6.78e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
UPK1A
Tbio
Novelty:  0.01748122
p_int:  0.999385121
p_ni:  0.000614852
p_wrong:  2.7e-8
Data Source:  BioPlex
CYB5B
Tbio
Novelty:  0.09395308
p_int:  0.999334246
p_ni:  0.000664112
p_wrong:  0.000001642
Data Source:  BioPlex
IFNLR1
Tbio
Novelty:  0.01990628
p_int:  0.999144192
p_ni:  0.000801147
p_wrong:  0.000054661
Data Source:  BioPlex
SLC22A9
Tbio
Family:  Transporter
Novelty:  0.02212992
p_int:  0.998825084
p_ni:  0.001160499
p_wrong:  0.000014417
Data Source:  BioPlex
HEATR3
Tbio
Novelty:  0.08367436
p_int:  0.998057385
p_ni:  0.001940079
p_wrong:  0.000002535
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
physical activity measurement
1
1
0
1
59.1
educational attainment
1
1
1
16.8
exercise
1
1
1
13.5
diet measurement
1
1
1
3.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
physical activity measurement
0
1
59.1
educational attainment
1
16.8
exercise
1
13.5
diet measurement
1
3.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
dpy-19 like C-mannosyltransferase 1
VGNC:14010
463346
Mouse
MGI:1915685
244745
Rat
RGD:1305822
315496
Dog
dpy-19 like C-mannosyltransferase 1
VGNC:54299
482395
Horse
dpy-19 like C-mannosyltransferase 1
VGNC:17301
100070313
Species
Name
OMA
EggNOG
Inparanoid
Chimp
dpy-19 like C-mannosyltransferase 1
Mouse
Rat
Dog
dpy-19 like C-mannosyltransferase 1
Horse
dpy-19 like C-mannosyltransferase 1
Publication Statistics
PubMed Score 5.09
PubMed score by year
PubTator Score 0.47
PubTator score by year
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Related Publications
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PMID
Year
Title