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Tdark
DPRX
Divergent paired-related homeobox

Protein Summary
Description
Putative transcription factor. Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DPRX homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376650
  • ENSP00000365838
  • ENSG00000204595
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.6
biological process
0.41
protein domain
0.41
cellular component
0.31
transcription factor
0.29


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
LEUTX
Tdark
Family:  TF
Novelty:  0.20538904
Score:  0.866
Data Source:  STRINGDB
TPRX1
Tbio
Novelty:  0.4834652
Score:  0.852
Data Source:  STRINGDB
LBX1
Tbio
Family:  TF
Novelty:  0.00550999
Score:  0.78
Data Source:  STRINGDB
VENTX
Tbio
Family:  TF
Novelty:  0.09005259
Score:  0.758
Data Source:  STRINGDB
RAX2
Tbio
Family:  TF
Novelty:  0.04942999
Score:  0.749
Data Source:  STRINGDB
SP140
Tbio
Family:  TF; Epigenetic
Novelty:  0.04734307
Score:  0.706
Data Source:  STRINGDB
NANOGNB
Tdark
Novelty:  0.97898116
Score:  0.669
Data Source:  STRINGDB
SUGCT
Tbio
Family:  Enzyme
Novelty:  0.0075902
Score:  0.664
Data Source:  STRINGDB
FAM91A1
Tbio
Novelty:  0.76982657
Score:  0.648
Data Source:  STRINGDB
PEPD
Tchem
Family:  Enzyme
Novelty:  0.00141261
Score:  0.643
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 5.18
PubMed score by year
PubTator Score 3.40
PubTator score by year
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Related Publications
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PMID
Year
Title