DNMT3L
DNA (cytosine-5)-methyltransferase 3-like
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.76 | ||
kinase perturbation | 0.66 | ||
PubMedID | 0.63 | ||
biological process | 0.58 | ||
cell type or tissue | 0.57 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA methylation | ||||
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA methylation | ||||
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 3 | 0 | 1.1 | 90.1 | |||||
Addison disease | 1 | 2 | 0 | 2.8 | 88.2 | ||||
eosinophil count | 3 | 2 | 3 | 85.1 | |||||
eosinophil percentage of leukocytes | 2 | 2 | 2 | 82.2 | |||||
1 | 1 | 0 | 1.1 | 77.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 90.1 | |||||
Addison disease | 0 | 2.8 | 88.2 | ||||
eosinophil count | 3 | 85.1 | |||||
eosinophil percentage of leukocytes | 2 | 82.2 | |||||
0 | 1.1 | 77.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | DNA methyltransferase 3 like | VGNC:14661 | 470099 | |||||
Macaque | DNA methyltransferase 3 like | 722184 | ||||||
Mouse | MGI:1859287 | 54427 | ||||||
Rat | RGD:1303239 | 309680 | ||||||
Dog | DNA methyltransferase 3 like | 608536 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | DNA methyltransferase 3 like | |||||
Macaque | DNA methyltransferase 3 like | |||||
Mouse | ||||||
Rat | ||||||
Dog | DNA methyltransferase 3 like | |||||
PMID | Year | Title |
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