Tbio DNLZ DNL-type zinc finger protein

Protein Summary

Description

May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation.

Uniprot Accession IDs

• Q5SXM8
• B2RUX5
• B9EJE1

Gene Name

• DNLZ

Ensembl ID

• ENST00000371738
• ENSP00000360803
• ENSG00000213221

Symbol

• C9orf151
• HEP
• HEP1
• ZIM17
• TIMM15
• C9orf151
• bA413M3.2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.73
transcription factor binding site profile	0.63
transcription factor perturbation	0.61
tissue sample	0.54
tissue	0.47

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.8   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 5   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.8   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0