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Tdark
DNAJC18
DnaJ homolog subfamily C member 18

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302060
  • ENSP00000302843
  • ENSG00000170464
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
tissue sample
0.75
virus perturbation
0.72
microRNA
0.62
disease perturbation
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.54   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 24   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.54   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (83)
CHRND
Tclin
Family:  IC
Novelty:  0.0441685
p_int:  0.999843428
p_ni:  0.000156572
Data Source:  BioPlex
RXFP1
Tchem
Family:  GPCR
Novelty:  0.00580827
p_int:  0.999378223
p_ni:  0.000621777
Data Source:  BioPlex
GABRD
Tclin
Family:  IC
Novelty:  0.0204242
p_int:  0.999253285
p_ni:  0.000746704
p_wrong:  1.1e-8
Data Source:  BioPlex
CHRNA9
Tchem
Family:  IC
Novelty:  0.05009815
p_int:  0.999206096
p_ni:  0.000793904
Score:  0.187
Data Source:  BioPlex,STRINGDB
IL27RA
Tbio
Novelty:  0.01348051
p_int:  0.998578355
p_ni:  0.001421645
Data Source:  BioPlex
KCNS3
Tclin
Family:  IC
Novelty:  0.05882087
p_int:  0.996038982
p_ni:  0.003961008
p_wrong:  9e-9
Data Source:  BioPlex
PCDHAC1
Tdark
Novelty:  0.3734734
p_int:  0.995990877
p_ni:  0.00400912
p_wrong:  3e-9
Score:  0.194
Data Source:  BioPlex,STRINGDB
GRIN2A
Tclin
Family:  IC
Novelty:  0.00060035
p_int:  0.995681423
p_ni:  0.004318577
Data Source:  BioPlex
FSHR
Tclin
Family:  GPCR
Novelty:  0.00123929
p_int:  0.994119605
p_ni:  0.005880395
Data Source:  BioPlex
TMEM63C
Tdark
Family:  IC
Novelty:  0.02849254
p_int:  0.98607288
p_ni:  0.013926859
p_wrong:  2.62e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin C measurement
1
1
1
86.9
1
1
0
1.2
72.1
viral load
1
1
1
66.8
electrocardiography
1
1
4
62.1
reticulocyte count
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin C measurement
1
86.9
0
1.2
72.1
viral load
1
66.8
electrocardiography
4
62.1
reticulocyte count
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member C18
VGNC:11930
462105
Macaque
DnaJ heat shock protein family (Hsp40) member C18
693952
Mouse
MGI:1923844
76594
Rat
RGD:1310237
291677
Dog
DnaJ heat shock protein family (Hsp40) member C18
VGNC:52130
606792
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member C18
Macaque
DnaJ heat shock protein family (Hsp40) member C18
Mouse
Rat
Dog
DnaJ heat shock protein family (Hsp40) member C18
Publication Statistics
PubMed Score 0.54
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title