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Tbio
DNAJC12
DnaJ homolog subfamily C member 12

Protein Summary
Description
This gene encodes a member of a subclass of the HSP40/DnaJ protein family. Members of this family of proteins are associated with complex assembly, protein folding, and export. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000225171
  • ENSP00000225171
  • ENSG00000108176
  • ENST00000339758
  • ENSP00000343575

Symbol
  • JDP1
  • JDP1
  • HPANBH4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.91
transcription factor perturbation
0.84
gene perturbation
0.83
cell type or tissue
0.77
PubMedID
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.36   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.36   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (83)
TH
Tclin
Family:  Enzyme
Novelty:  0.00025719
p_int:  0.999989971
p_ni:  0.000010029
Score:  0.186
Data Source:  BioPlex,STRINGDB
TPH1
Tclin
Family:  Enzyme
Novelty:  0.00098637
p_int:  0.999988505
p_ni:  0.000011495
Score:  0.324
Data Source:  BioPlex,STRINGDB
ANTXR1
Tbio
Novelty:  0.00508081
p_int:  0.999622161
p_ni:  0.000377838
Data Source:  BioPlex
ERI2
Tbio
Family:  Enzyme
Novelty:  0.10111379
p_int:  0.998030005
p_ni:  0.001969995
Score:  0.345
Data Source:  BioPlex,STRINGDB
TPH2
Tchem
Family:  Enzyme
Novelty:  0.00265377
p_int:  0.997770269
p_ni:  0.00222857
p_wrong:  0.000001162
Score:  0.388
Data Source:  BioPlex,STRINGDB
LIPH
Tbio
Family:  Enzyme
Novelty:  0.00961658
p_int:  0.993456651
p_ni:  0.006543306
p_wrong:  4.4e-8
Data Source:  BioPlex
ITLN1
Tbio
Novelty:  0.00299735
p_int:  0.989092322
p_ni:  0.010907676
p_wrong:  2e-9
Score:  0.19
Data Source:  BioPlex,STRINGDB
PLPPR2
Tdark
Family:  Enzyme
Novelty:  1.03318406
p_int:  0.989049221
p_ni:  0.010950779
Data Source:  BioPlex
ARL4C
Tbio
Family:  Enzyme
Novelty:  0.04764628
p_int:  0.988934752
p_ni:  0.011065247
p_wrong:  1e-9
Data Source:  BioPlex
PRMT6
Tchem
Family:  Epigenetic
Novelty:  0.01734208
p_int:  0.978428465
p_ni:  0.021571532
p_wrong:  3e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
2
2
73.4
mean platelet volume
2
2
2
64.8
leukocyte count
1
1
1
56.8
alkaline phosphatase measurement
1
1
1
45.7
sex hormone-binding globulin measurement
2
1
2
28
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
73.4
mean platelet volume
2
64.8
leukocyte count
1
56.8
alkaline phosphatase measurement
1
45.7
sex hormone-binding globulin measurement
2
28
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member C12
VGNC:12305
466287
Macaque
DnaJ heat shock protein family (Hsp40) member C12
695795
Mouse
MGI:1353428
30045
Rat
RGD:1591898
619393
Dog
DnaJ heat shock protein family (Hsp40) member C12
479224
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member C12
Macaque
DnaJ heat shock protein family (Hsp40) member C12
Mouse
Rat
Dog
DnaJ heat shock protein family (Hsp40) member C12
Publication Statistics
PubMed Score 25.36
PubMed score by year
PubTator Score 13.29
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title