You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
DIP2C
Disco-interacting protein 2 homolog C

Protein Summary
Description
This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000280886
  • ENSP00000280886
  • ENSG00000151240

Symbol
  • KIAA0934
  • KIAA0934
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
microRNA
0.76
trait
0.75
transcription factor
0.64
cell line
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.05   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 21   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.05   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 21   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
PIP4K2A
Tbio
Family:  Kinase
Novelty:  0.01130885
p_int:  0.999999989
p_ni:  8e-9
p_wrong:  3e-9
Score:  0.208
Data Source:  BioPlex,STRINGDB
STK32B
Tchem
Family:  Kinase
Novelty:  0.1892431
Score:  0.727
Data Source:  STRINGDB
LARP4B
Tbio
Novelty:  0.11363794
Score:  0.653
Data Source:  STRINGDB
ZMYND11
Tbio
Family:  Epigenetic
Novelty:  0.02485283
Score:  0.652
Data Source:  STRINGDB
CWH43
Tdark
Novelty:  0.14503432
Score:  0.579
Data Source:  STRINGDB
WDR37
Tbio
Novelty:  0.1677975
Score:  0.574
Data Source:  STRINGDB
KCNS2
Tclin
Family:  IC
Novelty:  0.51090552
Score:  0.565
Data Source:  STRINGDB
ZCCHC14
Tbio
Novelty:  0.18393973
Score:  0.558
Data Source:  STRINGDB
NAGPA
Tbio
Family:  Enzyme
Novelty:  0.03136768
Score:  0.528
Data Source:  STRINGDB
AASDH
Tbio
Family:  Enzyme
Novelty:  0.17181708
Score:  0.516
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
1
1
1
10.5
chronotype measurement
1
1
1
2.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
1
10.5
chronotype measurement
1
2.5
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
disco interacting protein 2 homolog C
721789
Mouse
MGI:1920179
208440
Rat
RGD:1560155
307067
Dog
disco interacting protein 2 homolog C
VGNC:49864
610591
Horse
disco interacting protein 2 homolog C
VGNC:17191
100071284
Species
Name
OMA
EggNOG
Inparanoid
Macaque
disco interacting protein 2 homolog C
Mouse
Rat
Dog
disco interacting protein 2 homolog C
Horse
disco interacting protein 2 homolog C
Publication Statistics
PubMed Score 9.05
PubMed score by year
PubTator Score 1.77
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title