DIABLO
Diablo homolog, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.99 | ||
disease perturbation | 0.98 | ||
chemical | 0.9 | ||
transcription factor perturbation | 0.88 | ||
biological term | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Apoptosis | ||||
Reactome | Apoptotic factor-mediated response | ||||
Reactome | Cytochrome c-mediated apoptotic response | ||||
Reactome | Formation of apoptosome | ||||
Reactome | Intrinsic Pathway for Apoptosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Apoptosis | ||||
Apoptotic factor-mediated response | ||||
Cytochrome c-mediated apoptotic response | ||||
Formation of apoptosome | ||||
Intrinsic Pathway for Apoptosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 11 | 12 | 90.9 | |||||
BMI-adjusted waist-hip ratio | 1 | 9 | 9 | 86.2 | |||||
waist-hip ratio | 1 | 9 | 9 | 84.2 | |||||
high density lipoprotein cholesterol measurement | 1 | 2 | 2 | 79.2 | |||||
serum alanine aminotransferase measurement | 1 | 1 | 0 | 10.3 | 76.8 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 12 | 90.9 | |||||
BMI-adjusted waist-hip ratio | 9 | 86.2 | |||||
waist-hip ratio | 9 | 84.2 | |||||
high density lipoprotein cholesterol measurement | 2 | 79.2 | |||||
serum alanine aminotransferase measurement | 0 | 10.3 | 76.8 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:1913843 | 66593 | ||||||
Rat | RGD:2321120 | 100360940 | ||||||
Dog | diablo IAP-binding mitochondrial protein | VGNC:39954 | 477463 | |||||
Horse | diablo IAP-binding mitochondrial protein | VGNC:17182 | 100058709 | |||||
Cow | diablo IAP-binding mitochondrial protein | VGNC:28061 | 493999 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | diablo IAP-binding mitochondrial protein | |||||
Horse | diablo IAP-binding mitochondrial protein | |||||
Cow | diablo IAP-binding mitochondrial protein | |||||
PMID | Year | Title |
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