You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
DHX57
Putative ATP-dependent RNA helicase DHX57

Protein Summary
Description
Probable ATP-binding RNA helicase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000457308
  • ENSP00000405111
  • ENSG00000163214

Symbol
  • DDX57
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
molecular function
0.99
virus perturbation
0.92
histone modification site profile
0.91
ligand (protein) perturbation
0.83


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (129)
SESN2
Tbio
Novelty:  0.00441857
p_int:  0.999995958
p_ni:  0.000003725
p_wrong:  3.17e-7
Score:  0.189
Data Source:  BioPlex,STRINGDB
APOD
Tbio
Novelty:  0.0031899
p_int:  0.999239114
p_ni:  0.000760886
Data Source:  BioPlex
DDX54
Tbio
Family:  Enzyme
Novelty:  0.12769464
p_int:  0.998601677
p_ni:  0.001398323
Score:  0.633
Data Source:  BioPlex,STRINGDB
ZDHHC17
Tbio
Family:  Enzyme
Novelty:  0.03288707
p_int:  0.998509241
p_ni:  0.001490759
Data Source:  BioPlex
CLU
Tbio
Novelty:  0.00054776
p_int:  0.998109936
p_ni:  0.001890064
Data Source:  BioPlex
RPS2
Tbio
Novelty:  0.00412313
p_int:  0.996681934
p_ni:  0.003318066
Score:  0.304
Data Source:  BioPlex,STRINGDB
H1FNT
Tdark
Novelty:  0.05593238
p_int:  0.996623291
p_ni:  0.003376709
Data Source:  BioPlex
FNTB
Tclin
Family:  Enzyme
Novelty:  0.07434994
p_int:  0.996215779
p_ni:  0.003784221
Data Source:  BioPlex
RPSA
Tbio
Novelty:  0.00250446
p_int:  0.995246671
p_ni:  0.004753329
Score:  0.653
Data Source:  BioPlex,STRINGDB
PRM2
Tbio
Novelty:  0.0050028
p_int:  0.995110015
p_ni:  0.004889985
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
DExH-box helicase 57
713523
Mouse
MGI:2147067
106794
Rat
RGD:1310340
366532
Dog
DExH-box helicase 57
VGNC:39950
483040
Horse
DExH-box helicase 57
VGNC:17180
100053939
Species
Name
OMA
EggNOG
Inparanoid
Macaque
DExH-box helicase 57
Mouse
Rat
Dog
DExH-box helicase 57
Horse
DExH-box helicase 57
Publication Statistics
PubMed Score 0.94
PubMed score by year
PubTator Score 1.09
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title