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Tdark
DHRSX
Dehydrogenase/reductase SDR family member on chromosome X

Protein Summary
Description
Involved in the positive regulation of starvation-induced autophagy (PubMed:25076851).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334651
  • ENSP00000334113
  • ENSG00000169084

Symbol
  • CXorf11
  • DHRS5X
  • SDR46C1
  • SDR7C6
  • DHRSY
  • DHRS5X
  • DHRS5Y
  • DHRSXY
  • SDR7C6
  • CXorf11
  • SDR46C1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.95
kinase perturbation
0.81
virus perturbation
0.64
transcription factor
0.63
disease perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.99   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.99   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (34)
ZBED1
Tbio
Family:  TF
Novelty:  0.01645222
p_int:  0.999999999
p_wrong:  1e-9
Score:  0.781
Data Source:  BioPlex,STRINGDB
GTPBP6
Tdark
Novelty:  0.05036884
Score:  0.696
Data Source:  STRINGDB
PLCXD1
Tdark
Novelty:  0.30611801
Score:  0.649
Data Source:  STRINGDB
ASMTL
Tbio
Family:  Enzyme
Novelty:  0.17725871
Score:  0.616
Data Source:  STRINGDB
SPRY3
Tbio
Novelty:  0.06114906
Score:  0.568
Data Source:  STRINGDB
FADS3
Tbio
Family:  Enzyme
Novelty:  0.02899077
Score:  0.536
Data Source:  STRINGDB
HEATR4
Tdark
Novelty:  4.22124175
Score:  0.531
Data Source:  STRINGDB
PCDH11X
Tbio
Novelty:  0.00588287
Score:  0.525
Data Source:  STRINGDB
N4BP2L1
Tdark
Novelty:  0.59201222
Score:  0.523
Data Source:  STRINGDB
ERMARD
Tdark
Novelty:  0.3424066
Score:  0.521
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2181510
236082
Dog
dehydrogenase/reductase X-linked
VGNC:54133
609792
Opossum
dehydrogenase/reductase X-linked
100010479
Platypus
dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399]
Chicken
dehydrogenase/reductase X-linked
CGNC:12501
428007
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
dehydrogenase/reductase X-linked
Opossum
dehydrogenase/reductase X-linked
Platypus
dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399]
Chicken
dehydrogenase/reductase X-linked
Publication Statistics
PubMed Score 3.99
PubMed score by year
PubTator Score 2.61
PubTator score by year
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Related Publications
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PMID
Year
Title