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Tbio
DEFB130A
Beta-defensin 130A

Protein Summary
Description
Antimicrobial host-defense peptide. Has an antiplasmodial activity. Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 8p23. [provided by RefSeq, Nov 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000400079
  • ENSP00000382951
  • ENSG00000232948
  • ENST00000646760
  • ENSP00000495606
  • ENSG00000285249

Symbol
  • DEFB130
  • DEFB30
  • DEFB30
  • DEFB-30
  • DEFB130
  • DEFB130L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.99   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.99   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0