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Tchem
DCUN1D5
DCN1-like protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260247
  • ENSP00000260247
  • ENSG00000137692

Symbol
  • SCCRO5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
virus perturbation
0.94
transcription factor perturbation
0.8
microRNA
0.79
transcription factor binding site profile
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.59   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 21   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.59   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 21   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Protein-Protein Interactions (209)
PNKD
Tbio
Family:  Enzyme
Novelty:  0.02456078
p_int:  0.999995883
p_ni:  0.000004115
p_wrong:  2e-9
Data Source:  BioPlex
TMEM206
Tdark
Novelty:  0.17311172
p_int:  0.999935065
p_ni:  0.000052423
p_wrong:  0.000012512
Data Source:  BioPlex
CYB5B
Tbio
Novelty:  0.09395308
p_int:  0.999915515
p_ni:  0.000084477
p_wrong:  7e-9
Data Source:  BioPlex
TGFA
Tbio
Novelty:  0.00216159
p_int:  0.999338126
p_ni:  0.000602494
p_wrong:  0.00005938
Data Source:  BioPlex
MAPK14
Tchem
Family:  Kinase
Novelty:  0.00045138
p_int:  0.989447839
p_ni:  0.010474296
p_wrong:  0.000077866
Data Source:  BioPlex
GNAI3
Tbio
Novelty:  0.03484857
p_int:  0.989447839
p_ni:  0.010474296
p_wrong:  0.000077866
Data Source:  BioPlex
CD70
Tbio
Novelty:  0.00420393
p_int:  0.983343511
p_ni:  0.016600849
p_wrong:  0.00005564
Data Source:  BioPlex
JTB
Tbio
Novelty:  0.06646216
p_int:  0.9790647
p_ni:  0.020932057
p_wrong:  0.000003243
Data Source:  BioPlex
TMEM213
Tdark
Novelty:  0.87036241
p_int:  0.959605111
p_ni:  0.04034421
p_wrong:  0.000050679
Score:  0.232
Data Source:  BioPlex,STRINGDB
ORMDL1
Tbio
Novelty:  0.1323746
p_int:  0.957974136
p_ni:  0.042000315
p_wrong:  0.000025549
Score:  0.209
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Neddylation
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Neddylation
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
matrix metalloproteinase 12 measurement
1
1
1
27.9
intraocular pressure measurement
1
1
1
17.8
waist-hip ratio
1
1
1
8.9
reticulocyte count
2
1
2
4.7
1
1
0
4
4.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
matrix metalloproteinase 12 measurement
1
27.9
intraocular pressure measurement
1
17.8
waist-hip ratio
1
8.9
reticulocyte count
2
4.7
0
4
4.6
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
defective in cullin neddylation 1 domain containing 5
VGNC:11336
451514
Macaque
defective in cullin neddylation 1 domain containing 5
704099
Mouse
MGI:1924113
76863
Rat
RGD:1307008
315405
Dog
defective in cullin neddylation 1 domain containing 5
VGNC:53330
487862
Species
Name
OMA
EggNOG
Inparanoid
Chimp
defective in cullin neddylation 1 domain containing 5
Macaque
defective in cullin neddylation 1 domain containing 5
Mouse
Rat
Dog
defective in cullin neddylation 1 domain containing 5
Publication Statistics
PubMed Score 2.59
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title