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Tdark
DCAF8L2
DDB1- and CUL4-associated factor 8-like protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000451261
  • ENSP00000462745
  • ENSG00000189186
  • ENST00000545306
  • ENSP00000479800

Symbol
  • WDR42C
  • WDR42C
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.54
cell line
0.48
chemical
0.41
protein domain
0.41
protein complex
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
ACAD11
Tbio
Family:  Enzyme
Novelty:  0.22908145
p_int:  0.999957881
p_ni:  0.000042119
Data Source:  BioPlex
CUL4A
Tchem
Novelty:  0.00917788
p_int:  0.999786613
p_ni:  0.000213387
Data Source:  BioPlex
TSPYL4
Tdark
Novelty:  0.4538252
p_int:  0.999631086
p_ni:  0.000364265
p_wrong:  0.000004648
Data Source:  BioPlex
CUL4B
Tbio
Novelty:  0.0133075
p_int:  0.999271641
p_ni:  0.000728359
Score:  0.158
Data Source:  BioPlex,STRINGDB
MYO5B
Tbio
Novelty:  0.01302142
p_int:  0.998322992
p_ni:  0.000718779
p_wrong:  0.000958229
Data Source:  BioPlex
P3H3
Tbio
Family:  Enzyme
Novelty:  0.0010004
p_int:  0.995629364
p_ni:  0.004370636
Data Source:  BioPlex
DDX52
Tbio
Family:  Enzyme
Novelty:  0.04618463
p_int:  0.986956665
p_ni:  0.012592889
p_wrong:  0.000450447
Data Source:  BioPlex
MICU1
Tbio
Novelty:  0.00984731
p_int:  0.985537972
p_ni:  0.014462028
Data Source:  BioPlex
DDB1
Tbio
Novelty:  0.00345896
p_int:  0.97640067
p_ni:  0.02359933
Score:  0.436
Data Source:  BioPlex,STRINGDB
MTPAP
Tbio
Family:  Enzyme
Novelty:  0.03447508
p_int:  0.975353795
p_ni:  0.024646205
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DDB1 and CUL4 associated factor 8 like 2
VGNC:12274
465551
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DDB1 and CUL4 associated factor 8 like 2
Publication Statistics
PubMed Score 0.11
PubMed score by year
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Related Publications
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PMID
Year
Title