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Tbio
DCAF15
DDB1- and CUL4-associated factor 15

Protein Summary
Description
May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254337
  • ENSP00000254337
  • ENSG00000132017

Symbol
  • C19orf72
  • C19orf72
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.75
histone modification site profile
0.69
disease perturbation
0.62
tissue
0.58
transcription factor perturbation
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.55   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 2   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.55   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 2   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0