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Tdark
DCAF10
DDB1- and CUL4-associated factor 10

Protein Summary
Description
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377724
  • ENSP00000366953
  • ENSG00000122741

Symbol
  • WDR32
  • WDR32
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.84
kinase perturbation
0.81
histone modification site profile
0.8
cell type or tissue
0.78
transcription factor binding site profile
0.78


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0