DBNL
Drebrin-like protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.81 | ||
kinase | 0.8 | ||
biological process | 0.78 | ||
transcription factor binding site profile | 0.75 | ||
tissue | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Apoptosis | ||||
Reactome | Apoptotic cleavage of cellular proteins | ||||
Reactome | Apoptotic execution phase | ||||
Reactome | Caspase-mediated cleavage of cytoskeletal proteins | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Apoptosis | ||||
Apoptotic cleavage of cellular proteins | ||||
Apoptotic execution phase | ||||
Caspase-mediated cleavage of cytoskeletal proteins | ||||
Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
HbA1c measurement | 1 | 2 | 2 | 89 | |||||
triglyceride measurement | 4 | 4 | 4 | 88.8 | |||||
glucose measurement | 1 | 1 | 1 | 79.7 | |||||
sex hormone-binding globulin measurement | 3 | 1 | 3 | 58.4 | |||||
4 | 2 | 2 | 1.1 | 56.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
HbA1c measurement | 2 | 89 | |||||
triglyceride measurement | 4 | 88.8 | |||||
glucose measurement | 1 | 79.7 | |||||
sex hormone-binding globulin measurement | 3 | 58.4 | |||||
2 | 1.1 | 56.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | drebrin like | VGNC:7374 | 463925 | |||||
Mouse | MGI:700006 | 13169 | ||||||
Rat | RGD:70941 | 83527 | ||||||
Dog | drebrin like | 607412 | ||||||
Horse | drebrin like | VGNC:17019 | 100051642 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | drebrin like | |||||
Mouse | ||||||
Rat | ||||||
Dog | drebrin like | |||||
Horse | drebrin like | |||||
PMID | Year | Title |
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