You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
DBNDD2
Dysbindin domain-containing protein 2

Protein Summary
Description
May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357275
  • ENSP00000349822
  • ENSG00000244274
  • ENST00000360981
  • ENSP00000354250
  • ENST00000372710
  • ENSP00000361795
  • ENST00000372712
  • ENSP00000361797
  • ENST00000372717
  • ENSP00000361802
  • ENST00000372720
  • ENSP00000361805
  • ENST00000372722
  • ENSP00000361807
  • ENST00000372723
  • ENSP00000361808

Symbol
  • C20orf35
  • CK1BP
  • HSMNP1
  • C20orf35
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor
0.7
PubMedID
0.68
gene perturbation
0.59
histone modification site profile
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.98   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.98   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (16)
PDXDC1
Tbio
Family:  Enzyme
Novelty:  0.16529476
Score:  0.742
Data Source:  STRINGDB
KITLG
Tbio
Novelty:  0.00036337
Score:  0.649
Data Source:  STRINGDB
DBNDD1
Tdark
Novelty:  0.60202124
Score:  0.611
Data Source:  STRINGDB
SYS1
Tbio
Novelty:  0.03311919
Score:  0.557
Data Source:  STRINGDB
TSTD1
Tdark
Family:  Enzyme
Novelty:  0.49753107
Score:  0.53
Data Source:  STRINGDB
MANBAL
Tdark
Novelty:  0.83071311
Score:  0.524
Data Source:  STRINGDB
DNM3
Tbio
Novelty:  0.02365643
Score:  0.517
Data Source:  STRINGDB
ZBTB34
Tdark
Family:  TF
Novelty:  0.5693361
Score:  0.501
Data Source:  STRINGDB
ZNF560
Tdark
Family:  TF
Novelty:  2.04576043
Score:  0.48
Data Source:  STRINGDB
ENTR1
Tbio
Novelty:  0.32267064
Score:  0.459
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
15
4
15
79.2
free cholesterol measurement
2
2
2
55.5
total cholesterol measurement
2
2
2
46.7
lipid measurement
2
2
2
46
phospholipids:total lipids ratio
2
2
2
35.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
15
79.2
free cholesterol measurement
2
55.5
total cholesterol measurement
2
46.7
lipid measurement
2
46
phospholipids:total lipids ratio
2
35.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
dysbindin domain containing 2
VGNC:9836
458281
Macaque
dysbindin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:15881]
Mouse
MGI:106562
52840
Rat
RGD:1559521
499941
Dog
dysbindin domain containing 2
VGNC:54645
477243
Species
Name
OMA
EggNOG
Inparanoid
Chimp
dysbindin domain containing 2
Macaque
dysbindin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:15881]
Mouse
Rat
Dog
dysbindin domain containing 2
Publication Statistics
PubMed Score 2.98
PubMed score by year
PubTator Score 1.69
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title