Tbio KLRF2 Killer cell lectin-like receptor subfamily F member 2

Protein Summary

Description

C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A.

Uniprot Accession IDs

• D3W0D1
• Lectin-like receptor F2

Gene Name

• KLRF2

Ensembl ID

• ENST00000535540
• ENSP00000438244
• ENSG00000256797

Symbol

• NKp65

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue	0.89
cell line	0.69
protein domain	0.41
phenotype	0.35
biological term	0.34

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.29   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 56   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.29   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0