CYP4F22
Cytochrome P450 4F22
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
pathway | 0.71 | ||
cell type or tissue | 0.65 | ||
gene perturbation | 0.65 | ||
molecular function | 0.53 | ||
tissue sample | 0.49 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Arachidonic acid metabolism | ||||
Reactome | Biological oxidations | ||||
Reactome | Cytochrome P450 - arranged by substrate type | ||||
Reactome | Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) | ||||
Reactome | Disease | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Arachidonic acid metabolism | ||||
Biological oxidations | ||||
Cytochrome P450 - arranged by substrate type | ||||
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) | ||||
Disease | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 1 | 4 | 4 | 80.5 | |||||
reticulocyte measurement | 1 | 1 | 1 | 44.2 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 10.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
lymphocyte count | 4 | 80.5 | |||||
reticulocyte measurement | 1 | 44.2 | |||||
monocyte percentage of leukocytes | 1 | 10.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | cytochrome P450 family 4 subfamily F member 22 | VGNC:7474 | 455798 | |||||
Macaque | cytochrome P450, family 4, subfamily F, polypeptide 22 | 718303 | ||||||
Mouse | MGI:2445210 | 320997 | ||||||
Rat | RGD:1308796 | 299566 | ||||||
Dog | cytochrome P450 family 4 subfamily F member 22 | VGNC:50366 | 484868 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | cytochrome P450 family 4 subfamily F member 22 | |||||
Macaque | cytochrome P450, family 4, subfamily F, polypeptide 22 | |||||
Mouse | ||||||
Rat | ||||||
Dog | cytochrome P450 family 4 subfamily F member 22 | |||||
PMID | Year | Title |
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