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Tdark
CYBC1
Cytochrome b-245 chaperone 1

Protein Summary
Description
Necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 hetrodimer. Controls the phagocyte respiratory burst and is essential for innate immunity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306645
  • ENSP00000307765
  • ENSG00000178927
  • ENST00000434650
  • ENSP00000401626
  • ENST00000437807
  • ENSP00000388909
  • ENST00000577436
  • ENSP00000464633
  • ENST00000577732
  • ENSP00000463228
  • ENST00000578919
  • ENSP00000464080
  • ENST00000585064
  • ENSP00000463846
  • ENST00000585080
  • ENSP00000462529

Symbol
  • C17orf62
  • EROS
  • Eros
  • C17orf62
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0