Tbio CYB5D2 Neuferricin

Protein Summary

Description

Heme-binding protein which promotes neuronal but not astrocyte differentiation.

Uniprot Accession IDs

• Q8WUJ1
• B2R7R6
• D3DTJ9
• I3L1K2

Gene Name

• CYB5D2

Ensembl ID

• ENST00000301391
• ENSP00000301391
• ENSG00000167740
• ENST00000575251
• ENSP00000458903
• ENST00000577075
• ENSP00000458352

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.77
virus perturbation	0.76
transcription factor binding site profile	0.72
tissue	0.64
tissue sample	0.64

Protein Classes

PANTHER Classes

Protein / Signaling Molecule / Neuferricin

Protein / Receptor / Neuferricin

DTO Classes

Protein / Signaling / Neuferricin

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.97   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 74   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.97   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0