Protein Summary
Heme-binding protein which promotes neuronal but not astrocyte differentiation.
- ENST00000301391
- ENSP00000301391
- ENSG00000167740
- ENST00000575251
- ENSP00000458903
- ENST00000577075
- ENSP00000458352
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.77 | ||
virus perturbation | 0.76 | ||
transcription factor binding site profile | 0.72 | ||
tissue | 0.64 | ||
tissue sample | 0.64 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.16 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 74 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.16 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 74 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (54)
NPTX2
Novelty: 0.00686292
p_int: 0.999999992
p_ni: 7e-9
Score: 0.214
Data Source: BioPlex,STRINGDB
AGTRAP
Novelty: 0.02295361
p_int: 0.999999841
p_ni: 6.5e-8
p_wrong: 9.4e-8
Score: 0.214
Data Source: BioPlex,STRINGDB
PTX3
Novelty: 0.00153752
p_int: 0.999999547
p_ni: 4.53e-7
Score: 0.188
Data Source: BioPlex,STRINGDB
ABLIM1
Novelty: 0.05511373
p_int: 0.999999488
p_ni: 5.12e-7
Score: 0.158
Data Source: BioPlex,STRINGDB
NPTXR
Novelty: 0.00727951
p_int: 0.999995395
p_ni: 0.000004598
p_wrong: 6e-9
Score: 0.228
Data Source: BioPlex,STRINGDB
GRIPAP1
Novelty: 0.09814766
p_int: 0.998756814
p_ni: 0.001243186
Score: 0.19
Data Source: BioPlex,STRINGDB
SLC30A5
Family: Transporter
Novelty: 0.02432633
p_int: 0.998342858
p_ni: 0.001657136
p_wrong: 6e-9
Data Source: BioPlex
POLDIP3
Family: Enzyme
Novelty: 0.03072373
p_int: 0.966584135
p_ni: 0.033415864
p_wrong: 1e-9
Score: 0.188
Data Source: BioPlex,STRINGDB
KLHL42
Novelty: 0.25822395
p_int: 0.962247715
p_ni: 0.037725468
p_wrong: 0.000026818
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (3)
Functions (1)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Disease Associations (null)
GWAS Traits (6)
Items per page:
1 – 5 of 6
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
10 | 7 | 4 | 1.1 | 95.5 | |||||
waist-hip ratio | 1 | 1 | 1 | 52 | |||||
hematocrit | 2 | 1 | 2 | 49.5 | |||||
heel bone mineral density | 2 | 2 | 2 | 49.2 | |||||
visceral adipose tissue measurement | 1 | 1 | 1 | 47.7 | |||||
Items per page:
1 – 5 of 6
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
4 | 1.1 | 95.5 | |||||
waist-hip ratio | 1 | 52 | |||||
hematocrit | 2 | 49.5 | |||||
heel bone mineral density | 2 | 49.2 | |||||
visceral adipose tissue measurement | 1 | 47.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:2684848 | 192986 | ||||||
Rat | RGD:1359124 | 303293 | ||||||
Dog | cytochrome b5 domain containing 2 | VGNC:50280 | 489437 | |||||
Horse | cytochrome b5 domain containing 2 | VGNC:50462 | 100060725 | |||||
Cow | cytochrome b5 domain containing 2 | VGNC:50262 | 515356 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | cytochrome b5 domain containing 2 | |||||
Horse | cytochrome b5 domain containing 2 | |||||
Cow | cytochrome b5 domain containing 2 | |||||
Publication Statistics
PubMed Score 6.16
PubMed score by year
PubTator Score 3.90
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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