CYB5B
Cytochrome b5 type B
Protein Summary
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
- ENST00000512062
- ENSP00000423679
- ENSG00000103018
- CYB5M
- OMB5
- OMB5
- CYB5-M
- CYPB5M
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 0.95 | ||
histone modification site profile | 0.88 | ||
transcription factor binding site profile | 0.88 | ||
transcription factor perturbation | 0.88 | ||
kinase perturbation | 0.81 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.43 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 70 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.43 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 70 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (137)
GDE1
Family: Enzyme
Novelty: 0.05854843
p_int: 0.999978897
p_ni: 0.000003035
p_wrong: 0.000018068
Data Source: BioPlex
DCUN1D5
Novelty: 0.56719852
p_int: 0.999915515
p_ni: 0.000084477
p_wrong: 7e-9
Data Source: BioPlex
MTOR
Family: Kinase
Novelty: 0.00012333
p_int: 0.999875524
p_ni: 0.000124476
Data Source: BioPlex
USP24
Family: Enzyme
Novelty: 0.07281326
p_int: 0.999820346
p_ni: 0.000179654
Data Source: BioPlex
KIAA0391
Family: Enzyme
Novelty: 0.02276396
p_int: 0.999548183
p_ni: 0.000451817
Data Source: BioPlex
XPO6
Novelty: 0.03229708
p_int: 0.999476655
p_ni: 0.000523345
Score: 0.203
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (5)
Reactome (3)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Metabolism | ||||
Reactome | Phase I - Functionalization of compounds | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Biological oxidations | ||||
Metabolism | ||||
Phase I - Functionalization of compounds | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (2)
Components (3)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (29)
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
urate measurement | 4 | 3 | 5 | 83 | |||||
body mass index | 5 | 2 | 5 | 80.5 | |||||
high density lipoprotein cholesterol measurement | 3 | 1 | 3 | 68.6 | |||||
daytime rest measurement | 1 | 1 | 1 | 55.2 | |||||
smoking initiation | 2 | 2 | 2 | 52.7 | |||||
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
urate measurement | 5 | 83 | |||||
body mass index | 5 | 80.5 | |||||
high density lipoprotein cholesterol measurement | 3 | 68.6 | |||||
daytime rest measurement | 1 | 55.2 | |||||
smoking initiation | 2 | 52.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | cytochrome b5 type B | VGNC:9029 | 454202 | |||||
Macaque | cytochrome b5 type B (outer mitochondrial membrane) | 705093 | ||||||
Mouse | MGI:1913677 | 66427 | ||||||
Rat | RGD:621551 | 80773 | ||||||
Horse | cytochrome b5 type B | VGNC:50460 | 100067168 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | cytochrome b5 type B | |||||
Macaque | cytochrome b5 type B (outer mitochondrial membrane) | |||||
Mouse | ||||||
Rat | ||||||
Horse | cytochrome b5 type B | |||||
Publication Statistics
PubMed Score 9.43
PubMed score by year
PubTator Score 7.20
PubTator score by year
Related Publications
Text Mined References (15)
GeneRif Annotations (7)
Items per page:
0 of 0
PMID | Year | Title |
|---|