Tbio CXCL9 C-X-C motif chemokine 9

Protein Summary

Description

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]

Uniprot Accession IDs

• Q07325
• Q503B4

Gene Name

• CXCL9

Ensembl ID

• ENST00000264888
• ENSP00000354901
• ENSG00000138755

Symbol

• CMK
• MIG
• SCYB9
• CMK
• MIG
• Humig
• SCYB9
• crg-10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.9
biological term	0.86
virus perturbation	0.85
disease	0.64
tissue sample	0.64

Protein Classes

PANTHER Classes

Protein / Signaling Molecule / Cytokine / Chemokine / C-x-c Motif Chemokine 9

DTO Classes

Protein / Signaling / Chemokine / C-x-c Motif Chemokine 9

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1742.45   (req: < 5)

Gene RIFs: 173   (req: <= 3)

Antibodies: 564   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1742.45   (req: >= 5)

Gene RIFs: 173   (req: > 3)

Antibodies: 564   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 24

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0