CXCL3
C-X-C motif chemokine 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 1 | ||
virus perturbation | 0.99 | ||
histone modification site profile | 0.82 | ||
small molecule perturbation | 0.79 | ||
cell type or tissue | 0.66 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chemokine receptors bind chemokines | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | GPCR ligand binding | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chemokine receptors bind chemokines | ||||
Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
GPCR ligand binding | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil count | 5 | 4 | 5 | 98.1 | |||||
myeloid white cell count | 3 | 3 | 3 | 96.1 | |||||
neutrophil percentage of leukocytes | 2 | 2 | 2 | 90.2 | |||||
lymphocyte percentage of leukocytes | 2 | 2 | 2 | 89.7 | |||||
leukocyte count | 4 | 2 | 4 | 89.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil count | 5 | 98.1 | |||||
myeloid white cell count | 3 | 96.1 | |||||
neutrophil percentage of leukocytes | 2 | 90.2 | |||||
lymphocyte percentage of leukocytes | 2 | 89.7 | |||||
leukocyte count | 4 | 89.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | C-X-C motif chemokine ligand 3 | VGNC:8662 | 461255 | |||||
Mouse | MGI:108068 | 14825 | ||||||
Cow | chemokine (C-X-C motif) ligand 2 | 281214 | ||||||
Opossum | growth-regulated alpha protein | 100023783 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | C-X-C motif chemokine ligand 3 | |||||
Mouse | ||||||
Cow | chemokine (C-X-C motif) ligand 2 | |||||
Opossum | growth-regulated alpha protein | |||||
PMID | Year | Title |
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