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Tbio
CUEDC1
CUE domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360238
  • ENSP00000353373
  • ENSG00000180891
  • ENST00000407144
  • ENSP00000384712
  • ENST00000577830
  • ENSP00000462717
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.81
cellular component
0.79
kinase perturbation
0.76
transcription factor perturbation
0.68
PubMedID
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
TOM1L1
Tbio
Novelty:  0.09426366
p_int:  0.999999973
p_ni:  2.3e-8
p_wrong:  4e-9
Score:  0.627
Data Source:  BioPlex,STRINGDB
STXBP4
Tbio
Novelty:  0.08831326
p_int:  0.99999917
p_ni:  8.3e-7
Score:  0.43
Data Source:  BioPlex,STRINGDB
HECW2
Tbio
Family:  Enzyme
Novelty:  0.07194044
p_int:  0.999994398
p_ni:  0.000005602
Data Source:  BioPlex
RBPJ
Tchem
Family:  TF
Novelty:  0.00168834
p_int:  0.999692734
p_ni:  0.000299929
p_wrong:  0.000007337
Data Source:  BioPlex
ZNF114
Tdark
Family:  TF
Novelty:  1.1380597
p_int:  0.999076954
p_ni:  0.000923045
Score:  0.193
Data Source:  BioPlex,STRINGDB
PPP4R3B
Tbio
Family:  Enzyme
Novelty:  0.0185504
p_int:  0.998436343
p_ni:  0.001563657
Data Source:  BioPlex
WWP1
Tbio
Family:  Enzyme
Novelty:  0.01407874
p_int:  0.997399853
p_ni:  0.002600147
Data Source:  BioPlex
FAM189B
Tbio
Novelty:  0.21064304
p_int:  0.997366147
p_ni:  0.002633853
Data Source:  BioPlex
RDH13
Tbio
Family:  Enzyme
Novelty:  0.20184998
p_int:  0.99704077
p_ni:  0.00295923
Data Source:  BioPlex
NHLH2
Tbio
Family:  TF
Novelty:  0.04744703
p_int:  0.995708027
p_ni:  0.004291973
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
33.1
gut microbiome measurement
1
1
2
24.5
body mass index
2
1
2
7.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
33.1
gut microbiome measurement
2
24.5
body mass index
2
7.7
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CUE domain containing 1
VGNC:9419
455152
Macaque
CUE domain containing 1
708927
Mouse
MGI:2144281
103841
Rat
RGD:1304861
303419
Dog
CUE domain containing 1
VGNC:39726
491105
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CUE domain containing 1
Macaque
CUE domain containing 1
Mouse
Rat
Dog
CUE domain containing 1
Publication Statistics
PubMed Score 5.72
PubMed score by year
PubTator Score 3.33
PubTator score by year
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Related Publications
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PMID
Year
Title