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Tbio
CTTNBP2NL
CTTNBP2 N-terminal-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000271277
  • ENSP00000271277
  • ENSG00000143079

Symbol
  • KIAA1433
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
drug perturbation
0.87
transcription factor perturbation
0.8
transcription factor binding site profile
0.78
histone modification site profile
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.54   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.54   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
STRN3
Tbio
Novelty:  0.10331283
p_int:  0.999999917
p_ni:  8.3e-8
Score:  0.942
Data Source:  BioPlex,STRINGDB
STRIP2
Tbio
Novelty:  0.19321125
p_int:  0.999998591
p_ni:  0.000001409
Score:  0.958
Data Source:  BioPlex,STRINGDB
STRN
Tbio
Novelty:  0.01025814
p_int:  0.999997694
p_ni:  0.000002306
Score:  0.954
Data Source:  BioPlex,STRINGDB
PPP2CB
Tbio
Family:  Enzyme
Novelty:  0.0483178
p_int:  0.999995617
p_ni:  0.000004382
p_wrong:  1e-9
Score:  0.882
Data Source:  BioPlex,STRINGDB
YPEL1
Tbio
Novelty:  0.17068379
p_int:  0.999950898
p_ni:  0.000049102
Score:  0.228
Data Source:  BioPlex,STRINGDB
PRDM14
Tbio
Family:  TF; Epigenetic
Novelty:  0.01776592
p_int:  0.999942384
p_ni:  0.000057616
Data Source:  BioPlex
PIP
Tbio
Novelty:  0.00208509
p_int:  0.999524701
p_ni:  0.000475299
Data Source:  BioPlex
STK25
Tchem
Family:  Kinase
Novelty:  0.03229688
p_int:  0.999148845
p_ni:  0.000851155
Score:  0.904
Data Source:  BioPlex,STRINGDB
PPP2R1A
Tbio
Family:  Enzyme
Novelty:  0.01134139
p_int:  0.998856509
p_ni:  0.001143491
Score:  0.89
Data Source:  BioPlex,STRINGDB
SPINK2
Tdark
Family:  Enzyme
Novelty:  0.06832697
p_int:  0.997236221
p_ni:  0.002763779
Score:  0.179
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
4
7
96.6
diastolic blood pressure
5
3
6
94
1
2
2
87
body fat distribution
2
1
3
81.1
systolic blood pressure
3
1
3
80.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
7
96.6
diastolic blood pressure
6
94
2
87
body fat distribution
3
81.1
systolic blood pressure
3
80.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CTTNBP2 N-terminal like
VGNC:1225
457104
Macaque
CTTNBP2 N-terminal like
705295
Mouse
MGI:1933137
80281
Rat
RGD:1310822
310760
Dog
CTTNBP2 N-terminal like
VGNC:39720
483222
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CTTNBP2 N-terminal like
Macaque
CTTNBP2 N-terminal like
Mouse
Rat
Dog
CTTNBP2 N-terminal like
Publication Statistics
PubMed Score 1.54
PubMed score by year
PubTator Score 1.54
PubTator score by year
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Related Publications
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PMID
Year
Title