Tdark CTRB2 Chymotrypsinogen B2

Protein Summary

Uniprot Accession IDs

• Q6GPI1
• A8K707

Gene Name

• CTRB2

Ensembl ID

• ENST00000303037
• ENSP00000303963
• ENSG00000168928

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.83
gene perturbation	0.67
cell type or tissue	0.58
protein domain	0.58
tissue	0.52

Protein Classes

PANTHER Classes

Protein / Hydrolase / Protease / Serine Protease / Chymotrypsinogen B2

DTO Classes

Protein / Enzyme / Protease / Serine Protease / Chymotrypsinogen B2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.91   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 0   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.91   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0