Protein Summary
May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.
- ENST00000343114
- ENSP00000341500
- ENSG00000066032
- ENST00000402739
- ENSP00000384638
- ENST00000466387
- ENSP00000418191
- ENST00000496558
- ENSP00000419295
- ENST00000541047
- ENSP00000444675
- ENST00000629316
- ENSP00000486160
- CAPR
- CAPR
- CTNR
- CAP-R
- CT114
- CDCBM9
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 1 | ||
gene perturbation | 0.9 | ||
hub protein | 0.75 | ||
kinase | 0.72 | ||
disease | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 253.01 (req: < 5)
Gene RIFs: 15 (req: <= 3)
Antibodies: 113 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 253.01 (req: >= 5)
Gene RIFs: 15 (req: > 3)
Antibodies: 113 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0