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Tbio
CTDSPL2
CTD small phosphatase-like protein 2

Protein Summary
Description
Probable phosphatase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260327
  • ENSP00000260327
  • ENSG00000137770
  • ENST00000558373
  • ENSP00000453051
  • ENST00000558966
  • ENSP00000452837

Symbol
  • HSPC058
  • HSPC129
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
1
histone modification site profile
0.89
microRNA
0.81
transcription factor binding site profile
0.78
transcription factor perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.55   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 126   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.55   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 126   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
PDIK1L
Tdark
Family:  Kinase
Novelty:  0.4630487
p_int:  0.999999999
Score:  0.554
Data Source:  BioPlex,STRINGDB
STK35
Tchem
Family:  Kinase
Novelty:  0.19556072
p_int:  0.999999996
p_ni:  3e-9
p_wrong:  1e-9
Score:  0.298
Data Source:  BioPlex,STRINGDB
ZCCHC10
Tdark
Novelty:  0.48625249
Score:  0.707
Data Source:  STRINGDB
TMEM135
Tdark
Novelty:  0.12811625
Score:  0.674
Data Source:  STRINGDB
TMEM87A
Tdark
Novelty:  0.33614983
Score:  0.651
Data Source:  STRINGDB
TBC1D32
Tbio
Novelty:  0.25744084
Score:  0.634
Data Source:  STRINGDB
FAM49B
Tbio
Novelty:  0.02928708
Score:  0.607
Data Source:  STRINGDB
RADX
Tdark
Novelty:  0.0935142
Score:  0.599
Data Source:  STRINGDB
UBLCP1
Tchem
Family:  Enzyme
Novelty:  0.14438023
Score:  0.594
Data Source:  STRINGDB
USP38
Tbio
Family:  Enzyme
Novelty:  0.10350208
Score:  0.57
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (25)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
19
2
20
91.7
C-reactive protein measurement
2
2
2
88.3
high density lipoprotein cholesterol measurement
25
2
26
87.6
low density lipoprotein cholesterol measurement
8
2
8
80.8
cholesterol:total lipids ratio
7
2
7
77.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
20
91.7
C-reactive protein measurement
2
88.3
high density lipoprotein cholesterol measurement
26
87.6
low density lipoprotein cholesterol measurement
8
80.8
cholesterol:total lipids ratio
7
77.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CTD small phosphatase like 2
VGNC:2481
453390
Macaque
CTD small phosphatase like 2
711917
Mouse
MGI:1196405
329506
Rat
RGD:1309219
311368
Dog
CTD small phosphatase like 2
VGNC:39695
487531
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CTD small phosphatase like 2
Macaque
CTD small phosphatase like 2
Mouse
Rat
Dog
CTD small phosphatase like 2
Publication Statistics
PubMed Score 5.55
PubMed score by year
PubTator Score 4.93
PubTator score by year
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Related Publications
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PMID
Year
Title