Tbio CSPG5 Chondroitin sulfate proteoglycan 5

Protein Summary

Description

May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Uniprot Accession IDs

• O95196
• Q71M39
• Q71M40

Gene Name

• CSPG5

Ensembl ID

• ENST00000264723
• ENSP00000264723
• ENSG00000114646
• ENST00000383738
• ENSP00000373244
• ENST00000456150
• ENSP00000392096

Symbol

• CALEB
• NGC
• NGC

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.95
cellular component	0.84
PubMedID	0.75
kinase perturbation	0.71
biological process	0.69

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.54   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 228   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.54   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 228   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0