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Tbio
CSMD3
CUB and sushi domain-containing protein 3

Protein Summary
Description
Involved in dendrite development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297405
  • ENSP00000297405
  • ENSG00000164796
  • ENST00000343508
  • ENSP00000345799
  • ENST00000455883
  • ENSP00000412263

Symbol
  • KIAA1894
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
microRNA
0.73
phenotype
0.63
transcription factor
0.63
transcription factor binding site profile
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.64   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.64   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (64)
RHNO1
Tbio
Novelty:  0.03103
Score:  0.801
Data Source:  STRINGDB
ANXA13
Tbio
Novelty:  0.01534307
Score:  0.8
Data Source:  STRINGDB
TRPS1
Tbio
Family:  TF
Novelty:  0.0075626
Score:  0.765
Data Source:  STRINGDB
GRID2
Tbio
Family:  IC
Novelty:  0.00628904
Score:  0.688
Data Source:  STRINGDB
LDLRAD3
Tbio
Novelty:  0.16667448
Score:  0.688
Data Source:  STRINGDB
INTS2
Tbio
Novelty:  0.22178745
Score:  0.686
Data Source:  STRINGDB
ZHX2
Tbio
Family:  TF
Novelty:  0.01370086
Score:  0.662
Data Source:  STRINGDB
EXT1
Tbio
Family:  Enzyme
Novelty:  0.00355951
Score:  0.64
Data Source:  STRINGDB
HYDIN
Tbio
Novelty:  0.03318399
Score:  0.634
Data Source:  STRINGDB
DPH6
Tbio
Family:  Enzyme
Novelty:  0.15211179
Score:  0.623
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
insomnia measurement
1
1
0
1
15.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
insomnia measurement
0
1
15.1
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CUB and Sushi multiple domains 3
VGNC:899
464341
Macaque
CUB and Sushi multiple domains 3
700010
Mouse
MGI:2386403
239420
Dog
CUB and Sushi multiple domains 3
VGNC:39663
482016
Horse
CUB and Sushi multiple domains 3
VGNC:16904
100056748
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CUB and Sushi multiple domains 3
Macaque
CUB and Sushi multiple domains 3
Mouse
Dog
CUB and Sushi multiple domains 3
Horse
CUB and Sushi multiple domains 3
Publication Statistics
PubMed Score 24.64
PubMed score by year
PubTator Score 8.16
PubTator score by year
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Related Publications
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PMID
Year
Title