Tbio CRYZL1 Quinone oxidoreductase-like protein 1

Protein Summary

Description

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O95825
• B2RDX1
• B3KQ77
• Q96DY0
• Q9NVY7

Gene Name

• CRYZL1

Ensembl ID

• ENST00000381554
• ENSP00000370966
• ENSG00000205758
• ENST00000420072
• ENSP00000416315

Symbol

• 4P11
• 4P11
• QOH-1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.91
transcription factor binding site profile	0.82
gene perturbation	0.81
cell type or tissue	0.78
transcription factor	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.48   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 228   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.48   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 228   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0